Definition of relevant differences between treatment options is a specific and sensitive method for expressing the ‘meaningfulness’ of innovation in a specific disease area. Relevance procedures are performed from a clinical, economic and patient perspective.
The defined relevant differences need to be validated; not exclusively by evidence based facts but also by practice based facts. Validated relevant differences provide ‘decision drivers’ for health care payers and health care committees.
Europe-ExPro is an institute that identifies clinical, economic and patient related issues in certain disease areas that require an assessment by experts. Europe-ExPro brings forth expert procedures on these issues. The expert procedure aims to define the relevance between the new treatment option and the existing treatment options. This is done from different perspectives, such as clinical, economic or patient perspective. By evidence based and practice based methods the relevant differences are validated. The expert procedure results in a report for public use and a manuscript available for submission in an appropriate journal. The expert procedure is executed in an early stage when a new treatment option becomes available and guidelines do not provide information yet. The definition and validation of clinical, economic or patient relevance serves as a decision making tool for health authorities, health insurers and for professional societies in preparing guidelines.
For each disease area and specialized issue, Europe-ExPro identifies an Expert Group and an expert coordinator. Dependent on the issue, the expert procedure is executed on a national or European level. The Expert Group brings forth an assessment without interference by medical, pharmaceutical industries, health care payers or professional organizations.